Ayurveda management in premature ovarian insufficiency- A case study K P Vidya PG Scholar, Department of Prasutitantra and Streeroga, PNNM Ayurveda medical college and hospital, Cheruthuruthy, Trishur, Kerala, India Divya U Assistant Professor, Department of Prasutitantra and Streeroga, PNNM Ayurveda medical college and hospital, Cheruthuruthy, Trishur, Kerala, India Sithara Satheesan Assistant Professor, Department of Prasutitantra and Streeroga, PNNM Ayurveda medical college and hospital, Cheruthuruthy, Trishur, Kerala, India Keywords: Premature Ovarian Insufficiency, Ayurveda, Artavakshaya, Yoni purana, Yonipichu Abstract Premature ovarian insufficiency (POI) is defined as a cessation of ovarian function before the age of 40 years. It is associated with hypoestrogenism and loss of residual follicles, both of which lead to menstrual abnormalities, pregnancy failures, and decreased health-related quality of life. The prevalence of POI is estimated at 1% in the general population. The risk of premature ovarian insufficiency (POI) before the age of 40 years is 1 %. The aetiopathology of premature ovarian insufficiency in the majority of cases is unknown and is termed as spontaneous or idiopathic POI. This is a case with signs and symptoms of POI which was developed after the administration of GnRH agonist drugs as a part of treatment of endometriosis. In this single case study, a female of 33 years having complaints of absence of periods since 6 months treated with Ayurveda treatment with pre and post evaluation. The symptoms of secondary amenorrhoea, hot flashes, vaginal dryness and mood swings were relieved after Ayurveda medications and procedures. pdf Published 2021-06-28 Issue Vol 5 No 2 (2021): April-June 2021 Section Case Reports