Effect of Unani Formulations in the Management of Unexplained Primary Infertility- A Case Report Afifa Naaz PG Scholar, National Institute of Unani Medicine, Kottigepalya, Magadi road, Bangalore, Karnataka, India. http://orcid.org/0009-0008-9531-4884 Wajeeha Begum Professor, National Institute of Unani Medicine (NIUM), Kottigepalya, Magadi road, Bangalore, Karnataka, India. http://orcid.org/0000-0002-9332-7162 Ghulam Nabi Wani PG Scholar, National Institute of Unani Medicine (NIUM), Kottigepalya, Magadi road, Bangalore, Karnataka, India. http://orcid.org/0009-0006-5026-3943 Keywords: Safuf Moaene hamal, Unani, Unexplained primary infertility, Uqr Abstract Infertility (‘Uqr) is customarily defined as the inability to conceive after 1 year of regular unprotected intercourse. 30% of infertile couples worldwide are diagnosed with unexplained or idiopathic infertility and the problem is defined as the lack of an obvious cause for a couple's infertility and the females’ inability to get pregnant after at least 12 cycles of unprotected intercourse or after six cycles in women above 35 years of age for whom all the standard evaluations are normal. In unani literature various medications have been mentioned for infertility. Here we present a case of primary infertility. The couple were trying to conceive for a period of 3 years. Thorough physical and laboratory investigations were done to rule out the cause which came out as unexplained primary infertility. Unani medications like Safuf Moaene hamal, ma‘jūn-i-mocharas, Khamira gaozaban saada and Sharbat zanjabeel were given continuously for 3 months. Patient got conceived after receiving treatment for 3 months continously. Above mentioned medications have assisted in conception which contains Muqawwi-i- bah activities, chemical constituents like tannins, Lupeol, Shamimicin, withaferins, sitoindosides and various useful alkaloids and multivitamins. pdf Published 2024-03-21 Issue Vol 8 No 1 (2024): January-March 2024 Section Case Reports