An Ayurvedic Intervention for the Management of Premature Ovarian Insufficiency: A Case Report

Abstract

Premature Ovarian Insufficiency (POI), also known as Premature Ovarian Failure, is a condition where ovarian function ceases before the age of 40. This condition is characterized by a depletion of ovarian reserves and residual follicles, leading to a hypo estrogenic state. Patients may present with amenorrhea, menstrual irregularities, and infertility, which can significantly impact their quality of life. The prevalence of POI is estimated to be 1% of the female population. It is diagnosed by amenorrhea or oligomenorrhoea lasting at least four months and two separate measurements of follicle-stimulating hormone (FSH) levels exceeding 25 IU/l, taken four weeks apart. The underlying cause may be impaired germ cell migration during the intrauterine period or accelerated germ cell apoptosis, resulting in few or no follicles in the ovaries. This single case study details a 34-year-old female with a four-month history of absent periods and other associated symptoms. The study evaluates her response to an Ayurvedic treatment plan, recording symptomatic reduction from secondary amenorrhea, like hot flashes, vaginal dryness, and mood swings. The results suggest that POI can be effectively managed with Ayurvedic medications and procedures, offering an alternative to hormone replacement therapy (HRT) and its potential side effects.