Ayurvedic Management of Parkinson Plus Syndrome: A Single Case Report Vineesh V Professor & HOD, Department of Rasashastra and Bhaishajya Kalpana, PNNM Ayurveda Medical College and Hospital, Cheruthuruthy, Thrissur, Kerala, India Nimitha B PG Scholar, Department of Kayachikitsa, PNNM Ayurveda Medical College and Hospital, Cheruthuruthy, Thrissur, Kerala, India DOI: https://doi.org/10.70805/ija-care.v9i1.663 Keywords: Ayurveda, Parkinson Plus Syndrome, Pithaavritha vyaana, Syndopa Abstract Parkinson's disease (PD) is commonly described as a predominantly motor ailment that typically manifests after the age of 50 and is brought on by the death of dopaminergic neurons, particularly in the substantia nigra. Resting tremors, rigidity, akinesia/bradykinesia, and postural instability are some of the main symptoms of PD. Steele mentioned that different clinical variants of the disease occur as different parts of the brain are affected at various times and degrees. These are called Parkinson's plus syndromes. Here I am highlighting a case report of a 31-year-old female patient diagnosed with Parkinsons plus syndrome, with presenting complaints of whole body pain and burning sensation, general weakness, loss of balance, and backward falls for 10 years. She was taking syndopa tablet with a dose of 55mg seven times per day. As per Ayurveda perspective, the condition was pitaavrita vyana, and initially addressed the avarana of pitha by giving ama pachana drugs internally and karaskra ksheera dhara externally, when the avarana was cleared kevala vatika treatments were done. After 21 days of both external and internal treatments, the patient had considerable improvement in symptoms along with she was able to reduce the dose of syndopa from seven times to three times. pdf Published 2025-03-06 Issue Vol 9 No 1 (2025): January-March 2025 Section Case Reports